Pulmonary Aspergillosis: A Short Review

volume 2  , Issue 2  , Page 28 -  30
Document Type : Review Article
Abu Khalid Muhammad Maruf Raza 1   Mahfujun Nahar 2   Muhammad Rafiqul Islam 3   Zaman Ahmed 4  
1Assistant Professor of Pathology, Jahurul Islam Medical College, Kishoregonj, Bangladesh.
2Medical officer, Jahurul Islam Medical College Hospital, Kishoregonj, Bangladesh.
3Registerer, National Institute of ENT, Dhaka, Bangladesh.
4Assistant Professor of Pathology, Abdul Malek Ukil Medical College, Noakhali, Bangladesh.

Pulmonary aspergillosis refers to a spectrum of diseases resulting from Aspergillus becoming resident in the lung. These include invasive aspergillosis from angioinvasive disease, simple aspergilloma from inert colonization of pulmonary cavities, and chronic cavitary pulmonary aspergillosis from fungal germination and immune activation. Chronic pulmonary aspergillosis includes simple aspergilloma, which is occasionally complicated by life-threatening hemoptysis, and progressive destructive cavitary disease requiring antifungal therapy. Allergic bronchopulmonary aspergillosis occurs almost exclusively in patients with asthma or cystic fibrosis. Invasive aspergillosis is now recognized to occur in patients with critical illness without neutropenia and in those with mild degrees of immunosuppression, including from corticosteroid use in the setting of COPD. Improvement in outcomes for Aspergillus pulmonary syndromes requires that physicians recognize the varied and sometimes subtle presentations, be aware of populations at risk of illness, and institute potentially life-saving therapies early in the disease course.



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